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Joseph E. and Martha E. Kutscher DDRC Symposium

Joseph E. and Martha E. Kutscher DDRC Symposium

October 5 to October 6, 2017

Scott & White Medical Center - Temple • Temple, Texas

Program Agenda

Thursday, October 5, 2017

  • 7:30 a.m.

    Continental breakfast and registration

  • 8 a.m.

    Opening remarks and introduction

    Dr. Gianfranco Alpini, PhD
    Distinguished Professor
    Dr. Nicholas C. Hightower
    Centennial Chair of Gastroenterology
    Director, BSWH Digestive Diseases Research Center
    VA Senior Research Career Scientist, Central Texas Veteran’s Health Care System
    Texas A&M College of Medicine

     

    Paul B. Hicks, MD, PhD
    Vice Dean, Temple Campus
    Professor, Psychiatry and Behavioral Science
    Texas A&M College of Medicine

    Robert A Probe, MD
    Executive Vice President & Chief Medical Officer,
    Baylor Scott & White Health

     

    Olawale Fashina, MD, MHSA, CPE
    Chief of Staff
    Central Texas Veterans Health Care System

     

    Boon Chew, PhD
    Professor and Head
    Department of Nutrition and Food Science
    Texas A&M University

  • Hepatobiliary Homeostasis and Liver Fibrosis

    Moderators: Dr. Shekhar Gandhi and Lindsey Kennedy (PhD candidate)

    25-minute presentations followed by 5 minutes of discussion (total time 30 minutes)

  • 8:20 a.m.

    Cystic Fibrosis-Related Liver Disease: From Channellopathy to Autoinflammatory Cholangiopathy

    Mario Strazzabosco, MD, PhD, FAASLD, FACG
    Professor of Medicine, Internal Medicine
    Director, Yale Liver Cancer Program
    Deputy Director Yale Liver Center
    Yale School of Medicine

  • 8:50 a.m.

    The Homeostatic Role of Autophagy in the Liver

    Xiao-Ming Yin, MD, PhD, FAASLD
    Louis Y. Mazzini Professor of Pathology
    Professor of Medicine, Biochemistry and Molecular Biology
    Vice Chair for Clinical Pathology
    Department of Pathology and Laboratory Medicine
    Indiana University School of Medicine

  • 9:20 a.m.

    Modulation of Biliary Homeostasis During Aging

    Marco Marzioni, MD
    Associate Professor of Gastroenterology
    Clinic of Gastroenterology and Hepatology
    Ospedali Riuniti University Hospital
    Università Politecnica delle Marche
    Ancona, Italy

  • 9:50 a.m.

    Therapeutic Implications of Modulating Beta-Catenin in Cholestasis

    Kari Nejak-Bowen, PhD
    Assistant Professor
    Department of Pathology
    University of Pittsburgh School of Medicine

  • 10:20 a.m.

    Break

  • Hepatobiliary Homeostasis, Liver Fibrosis and GI Cancer

    Moderators:  Drs. Kari-Nejak Bowen and Matthew McMillin
    25-minute presentations followed by 5 minutes of discussion (total time 30 minutes)

  • 10:30 a.m.

    Modeling Human HCC for Precision Therapy

    Satdarshan (Paul) S. Monga, MD
    Vice Chair of Experimental Pathology
    Endowed Chair for Experimental Pathology
    Professor of Pathology & Medicine 
    Assistant Dean for the Medical Scientist Training Program
    University of Pittsburgh School of Medicine

  • 11 a.m.

    Cancer Stem Cells: The Hidden Mother of all Cells to Target

    Shrikant Anant, PhD
    Professor and Vice Chair of Research
    Department of Surgery and Cancer Biology
    Kansas Mason Professor for Cancer Research
    Walsh Professor for Cancer Prevention
    Associate Director, University of Kansas Cancer Center
    Kansas University School of Medicine

  • 11:30 a.m.

    Genomics-enabled Medicine for Cholangiocarcinoma (CCA)

    Harshil Dhruv, PhD
    Assistant Professor
    Department of Cancer and Cell Biology
    The Translational Genomics Research Institute

  • Keynote Scientific Lecture

    12 p.m.

    Interleukin-22: A Magic Potion for Epithelial Cell Repair from Bench to Bedside

    Bin Gao M.D., PhD, Chief
    Laboratory of Liver Diseases
    National Institute on Alcohol Abuse and Alcoholism
    National Institutes of Health

    Boxed lunch provided

  • Alcohol-induced Hepatobiliary Damage

    Moderators: Drs. Bin Gao and Fanyin Meng

    25-minute presentations followed by 5 minutes of discussion (total time 30 minutes)

  • 1 p.m.

    The Role of IL-17 Signaling in Alcohol-induced Liver/Brain injury

    Tatiana Kisseleva, PhD
    Assistant Adjunct Professor, Department of Surgery
    UC San Diego School of Medicine

  • 1:30 p.m.

    Secretin/Secretin Receptor Axis in the Modulation of Acohol-Induced Biliary Injury and Liver Fibrosis

    Gianfranco Alpini, PhD, AGAF, FAASLD
    Distinguished Professor of Medicine and Medical Physiology
    Dr. Nicholas C. Hightower Centennial Chair of Gastroenterology
    Director, BSWH Digestive Diseases Research Center
    VA Senior Research Career Scientist, Central Texas Veteran’s Health Care System
    Texas A&M College of Medicine

  • 2 p.m.

    Role of Pyruvate Dehydrogenase 4 in Insulin Resistance and Hepatic Steatosis

    Suthat Liangpunsakul, MD, MPH
    Associate Professor of Medicine, Biochemistry and Molecular Biology
    Division of Gastroenterology and Hepatology
    Department of Medicine
    Roudebush Veterans Administration Medical Center
    Indiana University School of Medicine

  • 2:30 p.m.

    Break

  • 2:50 p.m.

    The Role of Sphingosine Kinase 2 in Alcohol-Induced Liver Injury

    Huiping Zhou, PhD
    Professor, Department of Microbiology and Immunology
    Medical College of Virginia
    Virginia Commonwealth University

  • 3:20 p.m.

    Role of Transcription Factor Reprograming in Alcoholic Hepatitis

    Ramon Bataller, MD, PhD
    Professor of Medicine
    Chief of Hepatology
    Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition
    University of Pittsburgh School of Medicine

  • Poster Session and Wine/Cheese Reception

    Entertainment provided by Temple High School Jazz Cats directed by Brent Matheson

  • 4 p.m.

    Judges: Drs. David Dostal, Damir Nizamutdinov, Cindy Meininger, Catherine McNeal, Samuel Fulcher, Anatoliy Gashev, Rakeshwar Guleria
    Awards will be given for 1st, 2nd, 3rd for both basic and clinical posters

  • 5:20 p.m.

    Introduction

    Heather Francis, PhD
    Associate Professor of Medicine, Texas A&M College of Medicine
    Central Texas Veteran’s Health Care System

  • 5:25 p.m.

    Young Investigator podium presentations

    (15 min each including questions)

  • Keynote Address

    Introduction of Dr. Kisseleva by Heather Francis, PhD

  • 6:15 p.m.

    Inactivation of Hepatic Stellate Cells during Reversal of Liver Fibrosis

    Tatiana Kisseleva, PhD
    Associate Adjunct Professor, Department of Surgery
    UC San Diego School of Medicine

  • 7 p.m.

    Poster Awards and Adjournment

  • 7:30 p.m.

    Dinner

    Faculty and invited guests will meet for dinner at Cheeves Bros. Steakhouse in downtown Temple, Texas.

Friday, October 6, 2017

  • 7 a.m.

    Continental breakfast

  • Metabolic Syndromes, NAFLD AND NASH

    Moderators:  Drs. Chaodong Wu and Arianne Theiss

    25-minute presentations followed by 5 minutes of discussion (total time 30 minutes)

  • 7:30 a.m.

    Why Does the Liver Deactivate Fatty Acids?

    David E. Cohen, MD, PhD

    Vincent Astor Distinguished Professor of Medicine

    Chief, Division of Gastroenterology and Hepatology

    Joan & Sanford I. Weill Department of Medicine

    Weill Cornell Medicine

  • 8 a.m.

    Preventing Offspring Obesity and Non-Alcoholic Fatty Liver Disease by Maternal Methionine SWupplementation Via Epigenetic Modification

    Linglin Xie, MD, PhD

    Assistant Professor

    Department of Nutrition and Food Science

    Texas A&M University

  • 8:30 a.m.

    Role of Adenosine 2a Receptor in Pathophysiology of Non-Alcoholic Fatty Liver Disease

    Chaodong Wu, MD, PhD

    Associate Professor and Faculty Fellow of AgriLife Research

    Department of Nutrition and Food Science

    Texas A&M University

  • 9 a.m.

    From NAFLD to NASH to Cirrhosis: New Insights into Disease Mechanisms

    Ariel Feldstein, MD

    Professor of Pediatrics

    Chief, Division of Pediatric Gastroenterology,

    Hepatology, and Nutrition

    UC San Diego School of Medicine

    Scientific Founder, Jecure Therapeutics

  • 9:30 a.m.

    Break

  • Microbiota and Gut/Liver Axis and GI Disorders I

    Moderators:  Drs. Linglin Xie and Sharon DeMorrow

    25-minute presentations followed by 5 minutes of discussion (total time 30 minutes)

  • 9:40 a.m.

    Plants as a Bio-Renewable, Sustainable, Diversified Platform for the Production of Therapeutic Nanoparticles to Treat Inflammatory Bowel Disease

    Didier Merlin, PhD

    Professor, Institute for Biomedical Sciences

    Center for Diagnostics and Therapeutics

    Center for Inflammation, Immunity and Infection

    Georgia State University

    Research Career Scientist, Atlanta VA Health Care System

  • 10:10 a.m.

    Monitoring Bile Acid Transport in Real Time

    Waddah Alrefai, MD

    Professor of Medicine, Division of Gastroenterology and Hepatology

    Research Career Scientist, Jesse Brown VA Medical Center

    University of Illinois at Chicago  

  • 10:40 a.m.

    Mitochondrial Dysfunction and Paneth Cell Defects in Ileitis

    Arianne L. Theiss, PhD
    Associate Investigator

    Baylor Scott & White Research Institute

    Adjunct Assistant Professor

    Institute for Biomedical Studies, Baylor University

  • 11:10 a.m.

    Hepatic Stellate Cells Are the Nucleus of Acute Liver Injury

    Chandrashekhar Gandhi, PhD, FAASLD

    Professor, Gastroenterology, Hepatology and Nutrition, Cincinnati Children’s Hospital Medical Center

    Professor of Surgery

    Research Career Scientist, VA Cincinnati Medical Center

    University of Cincinnati College of Medicine

  • 11:45 a.m.

    Lunch

  • 12 p.m.

    Internal Medicine Grand Rounds

    Introduction by Dawn Sears, MD, FACG

    Chief of Gastroenterology

    Baylor Scott & White Health

     

  • New Therapies for Liver Fibrosis

    David A. Brenner, MD

    Vice Chancellor, UC San Diego Health Sciences
    Dean, UC San Diego School of Medicine

  • 1 p.m.

    Group Picture

  • Microbiota and Gut/Liver Axis and GI Disorders II

    Moderators:  Dr. Rhonda Souza and Laurent Ehrlich (M.D., Ph.D. candidate)

    25-minute presentations followed by 5 minutes of discussion (total time 30 minutes)

     

  • 1:10 p.m.

    Is Cirrhosis a Microbial Disease?

    Jasmohan S Bajaj, MBBS, MD, M.S. FAASLD, FACG, AGAF

    Division of Gastroenterology, Hepatology and Nutrition

    McGuire VA Medical Center

    Virginia Commonwealth University School of Medicine

  • GLP1 and VIP Nanomedicine as Novel Therapeutics for IBD

    1:40 p.m.

    Pradeep Dudeja, PhD

    Professor of Physiology, Director of Scholarly Activities

    Section of Gastroenterology & Hepatology, Medicine,

    Senior VA Research Career Scientist, Jesse Brown VAMC

    University of Illinois College of Medicine – Chicago

  • 2:10 p.m.

    Role of Microbiota and Lipid Rafts in Enteric Neurodegeneration

    Shanthi Srinivasan, MD, AGAF

    Chief of Gastroenterology, Atlanta VA Medical Center

    Professor of Medicine, Division of Digestive Diseases

    Emory University School of Medicine

  • 2:40 p.m.

    The Role of GERD-Induced Cytokines in the Pathogenesis of Reflux Esophagitis

    Rhonda F. Souza, MD, AGAF, FASGE

    Co-Director, Center for Esophageal Diseases

    Baylor University Medical Center at Dallas

    Investigator/Professor

    Co-Director, Center for Esophageal Research

    Baylor Scott & White Research Institute

    Adjunct Professor

    Sun Yat-Sen University, Guangzhou, China

    Baylor University Medical Center

    Center for Esophageal Research

  • 3:10 p.m.

    Break

  • Clinical Advances in GI-Related Disorders

    3:20 p.m.

    Total Pancreatectomy with Islet Auto Transplantation as a Treatment for Refractory Chronic Pancreatitis

    Bashoo Naziruddin, PhD

    Director and Adjunct Professor

    Institute of Biomedical Studies, Baylor University

    Islet Cell Laboratory

    Baylor University Medical Center

  • 3:50 p.m.

    MEN 1 Genetics and Surgical Management of Neuroendocrine Tumors of the Pancreas

    Terry C. Lairmore, MD, FACS

    Professor of Surgery

    Director, Division of Surgical Oncology

    Baylor Scott & White Healthcare

    Texas A&M College of Medicine

  • 4:20 p.m.

    Contemporary Challenges in Surgical Treatment of Liver Malignancies

    Scott Celinski, MD, FACS  
    Co- Director Pancreatic Cancer Research and Treatment Center 

    Baylor University Medical Center

    Clinical Assistant Professor

    Texas A&M College of Medicine

  • 5 p.m.

    Closing Remarks and Adjournment

    Gianfranco Alpini, PhD

    Director, BSWH Digestive Diseases Research Center

  • 5:15 p.m.

    Wine and Cheese Reception

    Temple Health and Bioscience District
    Hosted by Tami Annable

Location

Scott & White Medical Center - Temple

The conference will be held at the Mayborn Auditorium within the Texas A&M Medical Education Building on the Scott & White Medical Center - Temple campus.

The Scott & White Medical Center - Temple campus encompasses many hospital buildings, programs and office buildings. A variety of parking options are available, including valet.

Download campus map

Address
Texas A&M Medical Education Building
2401 S. 31st St.
Temple, TX 76508

Pignetti's

On Wednesday evening, faculty and invited guests may check in early and enjoy dinner at Pignetti's, an upscale, brick-and-stucco venue for Italian specialties and an extensive wine list.

More about the restaurant

Address
14 S. 2nd St.
Temple, TX 76501

Cheeves Bros. Steak House

On Thursday evening, faculty and invited guests will enjoy dinner at Cheeves Bros. Steak House, as swanky, Texas-themed chophouse showcasing USDA Prime steaks, seafood and an extensive wine list.

More about the restaurant

Address
14 E. Avenue A
Temple, TX 76501

Registration and Abstract Submission

Designed to share cutting edge knowledge about the digestive system diseases through the integration of basic and clinical science research to provide new strategies to diagnose, treat and cure diseases of the digestive tract.

We invite medical professionals — including medical students, research coordinators, residents, fellows, APPs, physicians and research scientists — to attend.

We are also accepting abstract submissions for poster or podium presentations. Deadline for submission is Aug. 31, 2017.

Discovering novel ideas and research findings regarding the digestive system and liver diseases.