Research Studies

 

This study aims to assess the effectiveness of a portable biofeedback device to reduce stress and increase resilience in Emergency Department and Intensive Care doctors, nurses, physician assistant, and nurse practitioners. PI: Mark Powers, PhD. 2019 to present. IRB: 019-266.

The purpose of this study is to evaluate whether utilizing the Memory Consolidation Disruption strategy and targeted psychoeducation together enhances the efficacy of preventing PTSD in individuals who have experienced a traumatic injury. PI: Mark Powers, PhD. 2019 to present. IRB: 019-167.

BUMC is collaborating with the Center for Brain Health to examine the effectiveness of the SMART program to improve higher-order thinking skills during the first few months (e.g. 3-6 months) post-TBI. PI: Mark Powers, PhD. 2019 to present. IRB: 019-063.

The primary aim of this study is to examine the burden of injuries resulting from use of motorized scooters on our trauma center, to better inform lawmakers and trauma systems of the potential public health risks associated with the introduction of these scooter share programs. PI: William Weber, MD. 2018 to present. IRB: 018-817.

The purpose of this multi-center study is to explore the current vaccination practices of trauma surgeons at Level I trauma centers in Texas after splenic angioembolization of trauma patients to help guide decision-making regarding management of splenic injuries. Site PI: Michael Foreman, MD. 2018 to present. IRB: 018-739.

This multi-center study seeks to determine the physiologic consequence of bowel discontinuity versus anastomosis after damage control laparotomy to determine differences in bowel ischemia, anastamotic dehiscence, abdominal sepsis, and mortality as well as to identify independent risk factors for outcome variables. Site PI: Jennifer Mooney, MD. 2018 to present. IRB: 018-193.

This single-center trial assesses the effect of blood loss and transfusion on antibiotic levels, with the goal of developing dosing and repeat dosing protocol of antibiotics for cardiothoracic surgery patients who have undergone massive transfusion. PI: Nathan Vaughan, MD. Grant: Cardiovascular Research Review Committee (CVRRC) of the Baylor Health Care System Foundation. 2018 to present. IRB: 018-193.

Because BUMC treated patients from a mass casualty incident during the July 7, 2016 Dallas Police Shooting, we were invited to participate in a study evaluating the wounding characteristics and medical interventions required to rescue patients who survived a civilian public mass shooting (CPMS) event to better understand the types of procedures and interventions needed to minimize death following CPMS. Site PI: Michael Foreman, MD. 2018 to present. IRB: 018-189.

BUMC is collaborating with the Garland Police Department to evaluate the efficacy of pairing a virtual reality program with a transcranial Alternating Current Stimulator® (tACS) for enhanced performance and sleep in police officers and staff. PI: Mark Powers, PhD. 2018 to present. IRB: 018-181.

BUMC, in collaboration with the Baylor Institute for Rehabilitation (BIR), is evaluating the efficacy of Prolonged Exposure (PE) Therapy for individuals with spinal cord injuries in an inpatient rehabilitation setting. PI: Mark Powers, PhD. Grant: Department of Health and Human Services (90IFRE0003-01-00). 2017 to present. IRB: 017-410.

This prospective, international, 29-center study is a collaboration with the American Association for the Surgery of Trauma (AAST). The aim of this study is to determine if embolization of patients without an identified source of bleeding from pelvic fractures would aid in hemorrhage control. PI: Jennifer Mooney, MD. 2017 to present. IRB: 017-394.

BUMC joined this multi-center study which seeks to provide a contemporary description of intensive care conditions, diagnoses, patterns, differences, and resource use for patients in trauma ICUs in order to describe models of care delivery, surgical conditions, ICU bed allocation, and staffing structures for trauma patients in the USA and determine their association, if any, with morbidity and mortality. Site PI: Michael Foreman, MD. 2017 to present. IRB: 017-306.

The primary aim of this study is to examine use of diluted liposomal bupivacaine (Exparel), compared to other local anesthetics, for appendectomy or cholecystectomy patients and their subsequent outcomes and opioid medication consumption. PI: Laura B Petrey, MD. 2017 to present. IRB: 017-245.

BUMC is collaborating with the RAND Corporation and University of Pennsylvania to conduct this prospective study examining pain and medication use among Hispanic and African-American patients following traumatic injury with the goal of identifying specific targets for intervention. PI: Mark Powers, PhD. Grant: National Institutes of Health (NIH: R01MD010372). 2017 to present. IRB: 017-144.

With the success of the Need For Trauma Intervention (NFTI) study in 2016, BUMC is spearheading a 38-center, national study to determine if NFTI is a better tool for triaging trauma patients. In implementing NFTI at BUMC, the trauma team, has better refined the trauma activation criteria and conserved resources. PI: Nakia Rapier, MSN. 2017 to present. IRB: 017-025.

BUMC is a participating site in this prospective, multicenter, observational study through the multidisciplinary Scientific Advisory Board of the Aortic Trauma Foundation (ATF) and American Association for the Surgery of Trauma (AAST). This study aims to capture key elements of blunt thoracic aortic injury diagnosis, management, outcomes from leading trauma institutions in the U.S. Site PI: William Shutze, MD. 2016 to present. IRB: 016-192.

This study seeks to determine if there is a difference in outcomes and readmission rates for acute biliary pancreatitis patients who have undergone surgical intervention, cholecystectomy or ERCP, based on either a downward trend in their pancreatic enzyme levels versus a complete return to normal in their pancreatic enzyme levels. PI: Geoffrey Funk, MD. 2015 to present. IRB: 015-274.

BUMC, in collaboration with the University of Washington, is participating in a 24-center, national trial evaluating the efficacy of inpatient PTSD and comorbidity screening and outpatient collaborative care model on trauma survivors' outcomes after hospitalization. PI: Ann Marie Warren, PhD. Grant: National Institute of Mental Health (NIMH: UH3MH106333). 2015 to present. IRB: 015-044.

Through a partnership with the Dallas-Fort Worth Hospital Council (DFWHC) Data Initiative, BUMC is working to identify and screen those at risk for readmission following traumatic injury and develop interventions to reduce that risk. PI: Laura B Petrey, MD. 2013 to present. IRB: 013-189.

This novel, prospective longitudinal study examines the psychological impact among family members, caregivers, and friends of trauma patients admitted to the Intensive Care Unit at BUMC. PI: Ann Marie Warren, PhD. Funding: The Ginger Murchison Traumatic Brain Injury Fund of the Baylor Health Care System Foundation. 2015 to present. IRB: 012-249.

This study seeks to measure the psychological experience of clinicians to identify factors associated with job satisfaction, professional quality of life, and overall wellbeing. Participants include providers of multiple disciplines, including primary care ambulatory clinicians, hospitalist clinicians, and specialist clinicians. PI: Ann Marie Warren, PhD. 2012 to present. IRB: 012-035.

BTOP was the first prospective, longitudinal study at BUMC to examine the impact of physical, psychological, and social factors on trauma patients' outcomes post-inpatient hospitalization. PI: Ann Marie Warren, PhD. Funding: The Stanley Seeger Fund of the Baylor Health Care System Foundation. 2012 to present. IRB: 012-028.