Uterus Transplantation provides a promising potential treatment for women with absolute uterine factor infertility (AUI). A woman with AUI cannot carry a pregnancy. She is either born without a uterus, had her uterus removed or has a nonfunctioning uterus.
In 2016, Baylor Scott & White Health affiliates Baylor University Medical Center and Baylor Scott & White Research Institute started a pioneering clinical trial to explore uterus transplantation with the goal of achieving a healthy pregnancy and live birth. Ten women received transplants, and in November 2017, the nation’s first baby was born to a woman who received a uterus transplant.
Baylor Scott & White Research Institute and Baylor University Medical Center opened the second phase of the uterus transplant clinical trial in November 2018. The transplant surgeries in the second phase are complete. Since the birth of the first baby in the trial, we have welcomed four additional babies to mothers who received a uterus transplant as part of the trial. Observations from the trial have provided a greater understanding of transplantation and supporting medical disciplines.
Please note eligibility and requirements have been updated since the first phase of this trial.
- Women with uterine factor infertility
- Ages 20-35, with working ovaries
- BMI of less than 30
- Cancer-free for at least five years
- Negative for HIV, hepatitis B and C, chlamydia, gonorrhea and herpes
- No history of diabetes
- Ages 30-50
- BMI of less than 30
- Cancer-free for last five years
- Negative for HIV, hepatitis, gonorrhea, chlamydia and herpes
- No history of hypertension or diabetes
A uterus can be donated from either a living or deceased donor. A living uterus donor has met any desire she has to do her own childbearing and gives her uterus for the purpose of transplantation to a female recipient. A deceased uterus donor is a female that is willing to donate her uterus after death. A uterus transplant or donation is not for everyone, and there is an extensive screening process prior to inclusion in the trial. If you are interested in uterus donation or to enroll for uterus transplant, please complete our online contact us form.
Patients interested in learning more about the process should visit BSWHealth.com/UterusTransplant.